Application of the [ -P] ATP kinase assay to study anabolic signaling in human skeletal muscle
نویسندگان
چکیده
Chris McGlory, Amanda White, Caroline Treins, Barry Drust, Graeme L. Close, Don P. M. MacLaren, Iain T. Campbell, Andrew Philp, Simon Schenk, James P. Morton, and D. Lee Hamilton Health & Exercise Sciences Research Group University of Stirling, Stirling, United Kingdom; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, California; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California; INSERM U845, Université Paris Descartes, Paris, France; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom; and School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom
منابع مشابه
Application of the [γ-32P] ATP kinase assay to study anabolic signaling in human skeletal muscle.
AMPK (AMP-dependant protein kinase)-mTORC1 (mechanistic target of rapamycin in complex 1)-p70S6K1 (ribosomal protein S6 kinase 1 of 70 kDa) signaling plays a crucial role in muscle protein synthesis (MPS). Understanding this pathway has been advanced by the application of the Western blot (WB) technique. However, because many components of the mTORC1 pathway undergo numerous, multisite posttran...
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